New Releases for the Year of the Horse! Shijiazhuang Sihua Pharmaceutical Group’s Guangxiang Pharmaceutical Receives Concurrent Approval for Two Active Pharmaceutical Ingredients: Metoclopramide Hydrochloride and Metoclopramide
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TIME:2026-03-10
On February 27, the active pharmaceutical ingredients metoclopramide hydrochloride and metoclopramide, developed by Hebei Guangxiang Pharmaceutical Co., Ltd. of Shijiazhuang Sihua Pharmaceutical Group, successfully had their registration status at the Center for Drug Evaluation of the National Medical Products Administration changed to “A,” thereby qualifying as APIs used in marketed dosage forms. Since the beginning of this year, the Group has received approval for a total of five new specialty API products.
According to available information, metoclopramide hydrochloride and metoclopramide are dopamine D2 receptor antagonists that also exhibit agonistic activity at serotonin 5-HT4 receptors, thereby promoting gastrointestinal motility. The primary indication for these agents is the control of emesis, and they are used to treat symptoms such as nausea, belching, gastric distension, and reflux esophagitis.
In recent years, the Group has anchored itself in both domestic and international markets, continuously deepening its integrated innovation strategy that combines active pharmaceutical ingredients (APIs) with finished dosage forms. It has driven the high-end development of injectables, the diversification of oral formulations, and the specialized advancement of APIs, gradually establishing a robust product portfolio spanning anti-infectives, antivirals, respiratory, neurological, renal, cardiovascular and cerebrovascular, gastrointestinal, anesthetic, and endocrine therapeutic areas. At the same time, leveraging process optimization and digital transformation, the Group has steadily strengthened its API quality and cost advantages, becoming a reliable partner for numerous formulation manufacturers. To date, the Group boasts 96 API products, including 54 under Guangxiang Pharmaceutical, thereby injecting strong momentum into the company’s innovative, high-quality growth.
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